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Cambridge Centre for Parkinson-Plus



My research focuses on the role of the unfolded protein response (UPR) specifically the PERK branch in neurodegenerative disease.  I am interested in understanding better the molecular architecture,  regulatory and signaling mechanisms which control PERK activity.  Using a combination of structural, biochemical and biophysical techniques my aim is to provide new insights into the role that PERK plays in regulating physiological responses associated with neurodegenerative diseases.

(Mallucci lab/UK Dementia Research Institute at the University of Cambridge)
Senior Research Associate
E-mail: ajb342[at]
Dr Adrian J. Butcher
Not available for consultancy