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Dr Caroline H. Williams-Gray

Dr Caroline H. Williams-Gray

MRC Clinician Scientist, John Van Geest Centre for Brain Repair, University of Cambridge

Honorary Consultant Neurologist, Cambridge University Hospitals NHS Trust

E-mail: chm27[at]cam.ac.uk

Website: http://thebarkerlab.co.uk/

John Van Geest Centre for Brain Repair
University of Cambridge
Forvie Site
Robinson Way

Cambridge CB2 0PY

Research Interests

My research aims to better define the clinical heterogeneity of Parkinson’s disease and to understand the neurobiological basis of this, with the ultimate goal of developing more targeted therapeutic strategies for different PD subtypes. Using epidemiological, functional MRI and genetic approaches, my work to date has defined and characterised distinct cognitive syndromes in PD, and developed prognostic tools for dementia risk and poor outcome which can be used for early stratification. My group is currently investigating the role of the immune system in mediating heterogeneity of outcome in PD, through clinicopathological work, PET neuroimaging and studies of peripheral immune function in PD patients.

Key Publications

Williams-Gray CH, Wijeyekoon RS, Scott KM, Hayat S, Barker RA, Jones JL. Abnormalities of age-related T cell senescence in Parkinson's disease. Journal of neuroinflammation. 2018 May 28;15(1):166.